An intriguing paper on the "Variability and memory of protein levels in human cells".
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17122776&query_hl=1&itool=pubmed_docsum

Might have important implications for 'phenotypic diversity/heterogeneity within populations of cells'.

Interesting new papers!

Here is a very good review on the state of knowledge regarding
"The complexity of the mammalian transcriptome"
Stefano Gustincich¹, Albin Sandelin², Charles Plessy³, Shintaro Katayama², Roberto Simone¹, Dejan Lazarevic¹, Yoshihide Hayashizaki⁴, and Piero Carninci^4*
J. Physiol, in press
http://jp.physoc.org/cgi/content/abstract/jphysiol.2006.115568v1?ck=nck
An analysis of recent data that has been focusing on the mechanisms of brain-specific transcription.



Another interesting paper on the prevalence of pseudo-messenger RNA's, transcribed from pseudogenes, within the mammalian transcriptome.
"Pseudo-Messenger RNA: Phantoms of the Transcriptome"
Martin C. Frith^1,2, Laurens G. Wilming³, Alistair Forrest², Hideya Kawaji¹, Sin Lam Tan^4,5, Claes Wahlestedt^6,7, Vladimir B. Bajic^4,5, Chikatoshi Kai¹, Jun Kawai^1,8, Piero Carninci^1,8, Yoshihide Hayashizaki^1,8, Timothy L. Bailey², Lukasz Huminiecki^6,9*
PLoS Genetics, in press
http://genetics.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pgen.0020023

2006 Nobel Prize for Medicine awarded to Andrew Z. Fire and Craig C. Mello for their discovery and work on RNA Interference - gene silencing by double stranded RNA.

http://nobelprize.org/nobel_prizes/medicine/laureates/2006/