Monday, February 18, 2008

RNA-mediated epigenetic programming of a genome-rearrangement pathway

A demonstration that DNA or RNA templates can orchestrate these genome rearrangements in Oxytricha

http://www.nature.com/nature/journal/v451/n7175/full/nature06452.html
RNA editing of micro RNAs

More intriguing evidence that miRNAs might be important targets of the A-to-I RNA editing machinery.

This study highlights the notion that for elucidating the function of miRNAs it is important to consider the possibility that the primary miRNA transcript may be modified altering the molecule's target spectrum.

http://www.sciencemag.org/cgi/content/abstract/315/5815/1137